Science and Research

Developed by Prof. Valter Longo, Director of both the Longevity Institute at the University of Southern California and The Program on Longevity and Cancer at IFOM in Milan, designed the FMD. Over 20 years of extensive preclinical and clinical studies sponsored by the National Institutes of Health (NIH) and conducted at the Longevity Institute and Diabetes and Obesity Research Institute of the University of Southern California (USC) resulted in the development of the first FMD® (ProLon®) which:

The ProLon Diet is the first and only clinically tested, scientific breakthrough in Fasting Mimicking technology that goes well beyond weight loss* when it comes to beneficial health effects. The 5 days of The ProLon Fasting Mimicking Diet puts the body into a fasting state that triggers the body’s own mechanism’s to recycle at the cellular level for rejuvenation from within. His research has shown that specific diets can mimic fasting, enabling the body to experience the rejuvenating effects of a prolonged fast.

Doctors recommend as a 5-day intervention to help lose weight*
Support healthy metabolic balance and rejuvenation from within
Triggers autophagy for the clean up of worn out cells
Helps target visceral fat for a trimmer waistline.
* In a clinical study, ProLon is shown over three cycles to help individuals lose
an average of 5.7 lbs and 1.6 inches off their waist circumference.

Precautions

Since ProLon is a low-calorie diet, please avoid the following during the 5-days of the program:

• Any strenuous exercising or activities that may consume a high level of calories.

• Extreme temperature environments like hot tubs and saunas, or driving long distances under strong sun or heat exposure.

• Since ProLon is a food based program, please stop the product should you experience any symptom of an allergic reaction such as a rash, change in voice, swelling or fever.

• If you feel light headed or faint, you should eat something or drink juice or consume a beverage with sugar.

• If your symptoms do not subside, please contact your physician or if you feel this is a life threatening emergency, call 911.

Who Should NOT Use ProLon®

• Children under the age of 18

• Women who are pregnant or nursing

• Individuals who are allergic to nuts or soy

• You have dietary restrictions or a fever, cough, diarrhea, or signs of an active infection

• If you are underweight BMI <18) per the chart below, or have experienced protein deficiency or are malnourished:
  4’11”-5’2” and under 100 pounds
  5’3”-5’4” and under 105 pounds
  5’5”-5’7” and under 115 pounds
  5’8”-5’10” and under 125 pounds
  5’11”-6’0” and under 135 pounds
  6’1”-6’4” and under 150 pounds

• Individuals diagnosed with serious medical condition or disease, unless approved in writing by a physician appropriately trained to treat that condition

• Individuals who have been severely weakened by a disease or medical procedure

• Individuals who are taking medications which may not be safely consumed with a calorie restricted diet unless authorized in writing by a licensed physician

• Individuals with Diabetes (type 1 and type 2), cardiovascular disease and cancer, unless approved in writing by a licensed physician. ProLon® should never be combined with glucose lowering drugs, such as metformin or insulin

• Fasting is prohibited for individuals with particular metabolic diseases, such as those affecting gluconeogenesis.

• Individuals with a history of significant cardiac disease, particularly uncompensated congestive heart failure NYHA grade 2 or more or LVEF <40% on any prior assessment

• Individuals with liver or kidney disorders that may be affected by the very low glucose and protein content of the diet

• Individuals with a history of syncope (fainting) with calorie restriction or other medical co-morbidities

• Individuals who have special dietary needs that are incompatible with the ProLon® meal plan